Are there any adverse effects following an injection?
Minor side effects such as soreness or bruising may appear at the site of the injection.
Flushing may occur commonly and appear as redness, feeling of warmth in the chest, upper arms, and face. It is not a serious concern and is usually because of cortisone use. It will subside on its own within 2-3 days.
Keep your rheumatologist informed regarding such reaction so that the dose and type of cortisone may be modified for subsequent injections. Due to the stimulating effects of cortisone, you may feel difficulty in falling asleep for a night or two following the injection.
If you develop a fever with chills, unusually severe discomfort, redness, and swelling at the joint injection site, seek immediate medical attention as these may be signs of infection.
Source: https://www.cedars-sinai.edu/