Does a lung transplant cure asthma?
Asthma is a chronic condition that does not have a cure.
A lung transplant cannot cure asthma, as this is a chronic obstructive pulmonary disease, but it can help some people manage their symptoms. However, doctors very rarely recommend lung transplants as a treatment for severe asthma, although this condition is listed as an indication for lung transplantation.
Only two patients have received lung transplants to date. Both of these patients suffered from asthma that resulted from genetic influences were atopic and had allergic responses to common antigens. Their asthma was progressive, severe, persistent and resistant to adjuvant immunosuppressive therapy and high-dose oral steroids.
Because conventional and experimental therapeutic strategies failed, the patients were listed for lung transplantation and received transplants of normal lungs shortly thereafter. Their lung function parameters are normal and they have not developed asthma up to three years after transplantation. These facts support the notion that asthma is a local disease.