Does a lung transplant cure asthma?

Asthma is a chronic condition that does not have a cure.

A lung transplant cannot cure asthma, as this is a chronic obstructive pulmonary disease, but it can help some people manage their symptoms. However, doctors very rarely recommend lung transplants as a treatment for severe asthma, although this condition is listed as an indication for lung transplantation.

Only two patients have received lung transplants to date. Both of these patients who suffered from asthma that resulted from genetic influences were atopic and had allergic responses to common antigens. Their asthma was progressive, severe, persistent, and resistant to adjuvant immunosuppressive therapy and high-dose oral steroids.

Because conventional and experimental therapeutic strategies failed, the patients were listed for lung transplantation and received transplants of normal lungs shortly thereafter. Their lung function parameters are normal and they have not developed asthma up to three years after transplantation. These facts support the notion that asthma is a local disease.

How do I know if I am eligible for a lung transplant?

To be a candidate for lung transplantation, you must meet some conditions, such as the following:

  • Have the biological age of 65 or less for a single lung transplant and 60 for a bilateral lung transplant. Independent of your chronological age, your physical condition must meet the condition of someone having these ages.
  • Have a poor prognosis (anticipated 18 to 24-month survival)
  • Have no other life-threatening diseases
  • Have a good rehabilitation potential
  • Have emotional stability and a deep understanding of the implications
  • Have a social support system

Once all the medical procedures are completed and after reviewing your information, the members of the transplant team make a recommendation about treating your lung disease. They may suggest other therapies or further testing before considering surgery. It is important to keep in mind that a lung transplant is not adequate surgery for anyone with lung disease.


Disclaimer: We do not assume responsibility for the use of the provided information or its interpretation. Our efforts are towards providing current and reliable information; however these should not be considered, or used as a substitute for diagnosis or treatment.

Source: https://www.cedars-sinai.edu/Education/Medical-Library/